Objective This study evaluated the strategy of preserve counterlateral side non- infective system in treatment of isolated pacemaker pocket infection. Methods From Jan 2013 to Jun 2014

patients with isolated PM pocket infection

who were implanted a new system in counterlateral side

in Heart Center of Peking university People Hospital

were enrolled. All of the subjects were divided into two groups based on different treatment. Patients in test group were extracted system of infective side while preserve the non- infective system of counterlateral side. Patients in control group were extracted system of both sides. Follow up for at least 1year. To compare the recurrence of pocket infection in former infective side or of the new infection in counterlateral side. Results From Jan 2013 to Jun 2014

there were 45 patients with isolated PM pocket infection were enrolled

who were implanted a new system in counterlateral side. 23 cases were assigned into test group

22 in control group. The basic characteristics of both groups pre lead extraction shows that gender( male 60.8% vs. 54.5%

p<0.05)

age( 54.6±10.7 y vs. 57.1±8.9y

p<0.05)

duration from first implantation( 5.7±1.7y vs. 6.4±2.2y

p<0.05)

duration of pocket infection( 13.4±4.2m vs. 12.1±3.8m

p<0.05)

duration from implantation of new system( 7.4±2.9m vs. 9.1±3.7m

p<0.05). The patients in test group were extracted via superior vena cava in 19 cases while inferior vena cava in 4 cases. The patients in contol group were extracted via superior vena cava in 9 cases while inferior vena cava in 13 cases. There was significance in extract method between two groups. All of the cases in both groups were extracted system successfully

the acute success rate is 100%. There was no major complication in both groups. Post follow up of 1 year

there were no recurrence and new infection in both groups. Conclusions The method of extracting system of infective side while preserving the non- infective system of counterlateral side is a new appropriate strategy in treatment for patients with isolated PM pocket infection

in whom were implanted a new system in counterlateral side