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目的评价合并心力衰竭的常规起搏器患者升级为CRT逆转左室重构的作用。方法入选起搏依赖、合并心力衰竭的常规起搏器患者
将其升级为CRT。观察手术前后患者QRS时限、左室舒张末期内径(LVEDD)、射血分数(LVEF)与肺动脉收缩压(SPAP)等心脏结构和功能的变化情况。结果常规起搏器升级为CRT后
QRS时限较前明显缩短
由术前的155.2±27.1ms缩短至130±15.0ms
p<0.01。随访至术后6月
CRT有效率为68%(18/25例)
LVEDD[(64.6±8.5)vs(57.56±9.5)
p<0.01]显著缩小
LVEF[(29.4±3.8)vs(32.5±4.1)
p<0.01]显著增加
SPAP[(46.6±12.8)vs(44.5±13.1)
p<0.01]也较前下降。结论对于起搏依赖、合并心力衰竭的常规起搏器患者
升级为CRT可显著改善心功能、逆转心肌重构。
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