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目的探讨脂蛋白相关磷脂酶A
2
(Lp-PLA
2
)对行直接经皮冠状动脉介入治疗(PCI)的急性ST段抬高性心肌梗死(STEMI)患者预后的预测价值。方法连续入选2014年6月至2015年6月在河北省涿州市医院心内科住院治疗的首次急性心肌梗死患者共220例。入院根据PCI术前检测Lp-PLA
2
水平分为高、低水平两组
随访6个月
观察住院期间及随访期间心血管事件发生情况。结果高Lp-PLA
2
组在前壁心肌梗死、心功能killip≥Ⅱ分级比例、血肌酐(Cr)水平及冠脉病变支数高于低Lp-PLA
2
组
左室射血分数(LVEF)明显低于低Lp-PLA
2
组
6个月内预后比较有统计学意义(p
<
0.05)。结论脂蛋白相关磷脂酶A
2
对行直接PCI的急性STEMI患者6个月内发生心血管事件的预测有一定的价值。
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