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心率变异性是检测体内心脏自主神经功能的一种无创技术。众所周知
人体内环境的不稳定是心血管事件、心脏性猝死发生的重要原因
而自主神经功能的平衡又是人体内环境稳定的最重要因素。这使心率变异性检测对一般人群的健康保健
对不同特殊人群各种情况的评估
以及对心血管病患者的预后判断与心脏性猝死的预警都是一项重要的检查技术。心率变异性(Heart Rate Variability
HRV)的最早研发与应用始于1965年
那年
妇产科医生Hon和
Alvaro Alonso,Xuemei Huang,Thomas H. Mosley,Gerardo Heiss,Honglei Chen.Heart rate variability and the risk of P arkinson disease: The A therosclerosis R isk in C ommunities study[J].Ann Neurol.,2015(5).
Department of Biomedical Sciences for Health, University of Milan, Milan, Italy,IRCCS Galeazzi Orthopedic Institute, Milan, Italy,Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, IRCCS Istituto Auxologico Italiano, Milan, Italy,Department of Cardiothoracic, Vascular Anesthesia and Intensive Care, IRCCS Policlinico San Donato, Milan, Italy,Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois,Departments of Medicine and Pharmacology, Vanderbilt University, Nashville, Tennessee,Department of Internal Medicine, University of Stellenbosch, Stellenbosch, South Africa,Department of Internal Medicine, University of Stellenbosch, Stellenbosch, South Africa,Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, IRCCS Istituto Auxologico Italiano, Milan, Italy,Department of Molecular Medicine, University of Pavia, Pavia, Italy,Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, IRCCS Istituto Auxologico Italiano, Milan, Italy.Autonomic Control of Heart Rate and QT Interval Variability Influences Arrhythmic Risk in Long QT Syndrome Type 1[J].Journal of the American College of Cardiology,2015.
JUDITH N. TEN SANDE,PETER DAMMAN,JAN G.P. TIJSSEN,JORIS R. GROOT,REINOUD E. KNOPS,ARTHUR A.M. WILDE,PASCAL F.H.M. DESSEL.Value of Serial Heart Rate Variability Measurement for Prediction of Appropriate ICD Discharge in Patients with Heart Failure[J].J Cardiovasc Electrophysiol,2014(1).
F. Roosevelt Gilliam,Jagmeet P. Singh,Christopher M. Mullin,Maureen McGuire,Kellie J. Chase.Prognostic value of heart rate variability footprint and standard deviation of average 5-minute intrinsic R-R intervals for mortality in cardiac resynchronization therapy patients[J].Journal of Electrocardiology,2007(4).
Stefano Guzzetti,Ester Borroni,Pietro E. Garbelli,Elisa Ceriani,Paolo Della Bella,Nicola Montano,Chiara Cogliati,Virend K. Somers,Alberto Mallani,Alberto Porta.Symbolic Dynamics of Heart Rate Variability: A Probe to Investigate Cardiac Autonomic Modulation[J].Circulation,2005(4).
Azad Ghuran,Fiona Reid,Maria Teresa La Rovere,Georg Schmidt,J.Thomas Bigger,A.John Camm,Peter J Schwartz,Marek Malik.Heart rate turbulence-based predictors of fatal and nonfatal cardiac arrest (The autonomic tone and reflexes after myocardial infarction substudy)[J].The American Journal of Cardiology,2002(2).
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