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全世界第一个β受体阻滞剂(β阻滞剂)Pronethalol于1962年问世
研究表明
该药治疗冠心病心绞痛有效
但因存在明显的内在拟交感活性而未能用于临床。但James W Black于1988年因提出β阻滞剂的概念而获诺贝尔医学奖(图1)。诺贝尔奖评审委员会对他贡献的评价是:"自200年前发现洋地
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