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1. 武汉大学人民医院武汉大学心血管病研究所心血管病湖北省重点实验室
2. 武汉市江夏区第一人民医院
Published:2019
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[1]陈葵,陈霞,陈元秀,周纪宁,左进,葛健,晏寒,来欣.Ⅱ型Brugada心电图改变与IRBBB的鉴别[J].临床心电学杂志,2019,28(04):274-278+282.
Block Chen kui, Chen xia, Chen yuanxiu, et al. The Discrimination Between Brugada Type Ⅱ ECG Pattern and Incomplete Right Brunch Bundle Block[J]. 2019, 28(4): 274-278+282.
目的Ⅱ型Brugada综合征和不完全性右束支传导阻滞(IRBBB)的心电图表现类似
V1导联均呈r Sr’型
但是它们的发病机制和治疗方法、预后完全不同
本研究试图发现二者在心电图指标的不同
以期减少Ⅱ型Brugada综合征早期就诊时的漏诊和误诊。方法选择心电图诊断为IRBBB的心电图146例
根据ST段形态将其分为:(1)ST段抬高组
分为两个亚组:①马鞍形ST段抬高组
也即Ⅱ型Brugada综合征样心电图改变(21例);②非马鞍形ST段抬高组
也即IRBBB伴ST段抬高
(28例);(2)非ST段抬高组
也即IRBBB不伴ST段抬高(97例)
观察V1/V2S波上升肢与r’(或J波)下降肢之间的夹角(β角)
经r’顶点(或J波顶点)的垂直线与r’下降肢(或J波下降肢)之间的夹角(α角)以及β角与基线形成的基底的长度
与β角顶点5mm垂直线相交的基底线的长度。结果①ST段抬高组α角以及β角显著大于无ST段抬高组(17.9±9.2 vs 15.5±7.1
p<0.01
23.3±10.3 vs 20.8±9.0
p<0.05);②Ⅱ型Brugada心电图样改变组α角以及β角显著大于IRBBB伴ST段抬高组
(20.7±10.1 vs 15.8±7.2
p<0.05
25.6±11.3 vs 20.8±9.0
p<0.05)。结论 ST段抬高的形态与α角以及β角有关
马鞍型的ST段抬高的α角以及β角明显增大
可以此作为诊断和鉴别诊断Ⅱ型Brugada样心电图改变与不完全性右束支阻滞的客观依据之一。
Brugada Type Ⅱ ECG is featured with J wave and saddled-shaped ST segment elevation
that is often confused with the incomplete right bundle brunch block(IRBBB)which is also has a r’ wave and ST segment elevation. Objective Brugada Type Ⅱ ECG pattern and IRBBB have quite different treatment and recover result
we try to find some values for discriminating between them. Methods 146 patients who were diagnosed as IRBBB with V1 r Sr’ shape in the hospital were selected
they were divided in 2 groups according to the ST segment. Group A: ST segment elevation group
which was divided into 2 subgroups: ①Type Ⅱ Brugada ECG pattern(saddled-shaped ST-segment elevation
21 cases)
② IRBBB with ST-segment elevation( non saddled-shaped ST-segment elevation
28 cases). Group B: All patients without ST segment elevation
97 cases.Values were measured: ① α angle
the angle between the vertical line and downslope of r’wave. ② β angle
between the upslope of S-wave and downslope of r’wave. Results The mean values of α and β angle in ST segment elevation group were significantly bigger than in non-ST segment elevation group
(17.9±9.2 vs 15.5±7.1
p<0.01
23.3±10.3 vs 20.8±9.0
p<0.05). Type Ⅱ Brugada ECG pattern were significantly bigger than IRBBB with ST-segment elevation(20.7±10.1 vs 15.8±7.2
p<0.05
25.6±11.3 vs 20.8±9.0
p<0.05). Conclusions Saddled-ST segment elevation could increase α and β angle in V1/V2
that may be a method for discriminating between Brugada Type Ⅱ ECG pattern and IRBBB.
Brugada拟表型:一个新的临床实体 [J]. Byron H Gottschalk,Daniel D Anselm,Adrian Baranchuk,蒋祖勋. 实用心电学杂志 . 2015(04)
A Practical Approach to the Investigation of an rSr’ Pattern in Leads V 1 -V 2 [J] . Sahil Koppikar,Raimundo Barbosa-Barros,Adrian Baranchuk. Canadian Journal of Cardiology . 2015 (12)
Brugada ECG patterns in athletes [J] . Eugene H. Chung. Journal of Electrocardiology . 2015 (4)
Differential Diagnosis of rSr’ Pattern in Leads V1‐V2. Comprehensive Review and Proposed Algorithm [J] . Adrian Baranchuk,Andres Enriquez,Javier García‐Niebla,Antoni Bayés‐Genís,Roger Villuendas,Antoni Bayés de Luna. Ann Noninvasive Electrocardiol . 2015 (1)
Brugada Phenocopies: Consideration of Morphologic Criteria and Early Findings From an International Registry [J] . Daniel D. Anselm,Byron H. Gottschalk,Adrian Baranchuk. Canadian Journal of Cardiology . 2014 (12)
Current electrocardiographic criteria for diagnosis of Brugada pattern: a consensus report [J] . Antonio Bayés de Luna,Josep Brugada,Adrian Baranchuk,Martin Borggrefe,Guenter Breithardt,Diego Goldwasser,Pier Lambiase,Andrés Pérez Riera,Javier Garcia-Niebla,Carlos Pastore,Giuseppe Oreto,William McKenna,Wojciech Zareba,Ramon Brugada,Pedro Brugada. Journal of Electrocardiology . 2012 (5)
New Electrocardiographic Criteria for Discriminating Between Brugada Types 2 and 3 Patterns and Incomplete Right Bundle Branch Block [J] . Stéphane Chevallier,Andrei Forclaz,Joanna Tenkorang,Yannis Ahmad,Mohamed Faouzi,Denis Graf,Juerg Schlaepfer,Etienne Pruvot. Journal of the American College of Cardiology . 2011 (22)
Longer Repolarization in the Epicardium at the Right Ventricular Outflow Tract Causes Type 1 Electrocardiogram in Patients With Brugada Syndrome [J] . Satoshi Nagase,Kengo Fukushima Kusano,Hiroshi Morita,Nobuhiro Nishii,Kimikazu Banba,Atsuyuki Watanabe,Shigeki Hiramatsu,Kazufumi Nakamura,Satoru Sakuragi,Tohru Ohe. Journal of the American College of Cardiology . 2008 (12)
Automated detection of Brugada-type electrocardiogram using diagnostic criteria of the European Society of Cardiology and the American Heart Association [J] . Mutsuo Kaneko,Norimoto Isobe,Takashi Yamaki,Noboru Okamoto,Yoshihiko Watanabe,Tohru Iwatsuka,Tsuneharu Sakurai,Ryoji Kishi,Kiyoshi Nakazawa,Fumihiko Miyake. Journal of Electrocardiology . 2005 (4)
Delay in Right Ventricular Activation Contributes to Brugada Syndrome [J] . Raymond Tukkie,Peter Sogaard,Jim Vleugels,Irma K.L.M. de Groot,Arthur A.M. Wilde,Hanno L. Tan. Circulation: Journal of the American Heart Association . 2004 (10)
Cellular Basis for the Electrocardiographic J Wave [J] . Gan-Xin Yan,Charles Antzelevitch. Circulation . 1996 (2)
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