Correlation of HRV and blood catecholamine level in OSAHS patients

Mureti·abudixiaokuer; Feng yan

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Correlation of HRV and blood catecholamine level in OSAHS patients

更新时间：2025-10-15

- Correlation of HRV and blood catecholamine level in OSAHS patients
- Vol. 29, Issue 6, Pages: 431-435(2020)
- 作者机构：
  
  新疆维吾尔自治区人民医院
- 作者简介：
- 基金信息：
- DOI：
  CLC： R766
- Published：2020
- 稿件说明：
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[1]穆热提·阿卜迪肖库尔,冯艳.OSAHS患者HRV与血儿茶酚胺水平的相关性[J].临床心电学杂志,2020,29(06):431-435.

Mureti·abudixiaokuer, Feng yan. Correlation of HRV and blood catecholamine level in OSAHS patients[J]. 2020, 29(6): 431-435.
[1]穆热提·阿卜迪肖库尔,冯艳.OSAHS患者HRV与血儿茶酚胺水平的相关性[J].临床心电学杂志,2020,29(06):431-435. DOI：

Mureti·abudixiaokuer, Feng yan. Correlation of HRV and blood catecholamine level in OSAHS patients[J]. 2020, 29(6): 431-435. DOI：

摘要

目的探讨阻塞性睡眠呼吸暂停综合征（OSAHS）患者心率变异性、晨血儿茶酚胺的变化情况及其相关因素。方法选取2019年1月至10月因睡眠打鼾就诊于我院并完善多导睡眠监测（Polysomnography

PSG）诊断OSAHS患者173例为观察组

同期完善PSG但未达到OSAHS标准患者65例为对照组。分析两组患者在基线资料、PSG参数、心率变异性、甲氧基肾上腺素（MN）、甲氧基去甲肾上腺素（NMN）等方面的差异。根据呼吸暂停指数（AHI）将观察组分为轻中重三组后予以比较

最后进行年龄、AHI与心率变异性、晨血儿茶酚胺之间的相关性分析。结果观察组夜间平均血氧饱和度、LSaO2、PNN50%均明显小于对照组（p<0.05）

而AHI、MN、NMN均明显大于对照组（p<0.05）;重度组SDNN明显低于轻、中组

在PNN50%方面重、中度组明显小于轻度组（p<0.05）;重度OSAHS组患者MN水平明显高于轻、中度组（p<0.05）;重、中度OSAHS患者NMN水平明显高于轻度组（p<0.05）;OSAHS患者的年龄与SDNN、r MSSD、pNN50%呈负相关（p<0.05

p<0.01

p<0.05）

与NMN正相关（p<0.05）;OSAHS患者AHI与SDNN、pNN50%呈负相关（p<0.01

p<0.01）

与NMN呈正相关（p<0.05）。结论 OSAHS患者夜间有明显的交感-迷走紊乱

交感神经兴奋性增加

迷走神经张力降低

交感神经兴奋性与年龄、AHI有一定的相关性。

Abstract

Objective To study the changes and their correlation of heart rate variability

morning blood catecholamine in patients with OSAHS. Methods We selected 173 cases with OSAHS as observation group

65 patients who did not meet the OSAHS standard were the control group in our hospital from January to October 2019. The difference between the two groups in basic data

PSG indicators

heart rate variability

NMN w

ere analyzed. According to AHI

the observation was divided into three groups and completed the correlation analysis.Results The average blood oxygen saturation

LSaO

PNN50% of the observation were significantly less than the control group

But AHI

NMN were significantly larger than the control group; The SDNN of Severe group was lower than others

the pNN50% of Severe and Moderate were lower than Mild; The MN level in patients with Severe was significantly higher than Mild and Moderate

the NMN level of Severe and Moderate were higher than Mild; The age of OSAHS patients was negatively correlated with SDNN

rMSSD

pNN50%（p

0.05

0.01

0.05）

and positively correlated with NMN（p

0.05）

AHI of OSAHS patients was negatively correlated with SDNN and p NN50%（p

0.01

0.01）

and positively correlated with NMN（p

0.05）. Conclusions Patients with OSAHS have an obvious sympathetic-vagal disorder at night. Increased sympathetic excitability and Reduced vagal tone.It has obvious correlation with age and AHI.

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references

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