The relationship between increased heart rate and autonomic nerve function in patients with hypertension

Bai mei; Yuan zhiming; Zhang pu

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The relationship between increased heart rate and autonomic nerve function in patients with hypertension

更新时间：2025-10-15

- The relationship between increased heart rate and autonomic nerve function in patients with hypertension
- Issue 5, Pages: 356-358(2021)
- 作者机构：
  
  山西省太原安定医院
- 作者简介：
- 基金信息：
- DOI：
  CLC： R544.1
- Published：2021
- 稿件说明：
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Bai mei, Yuan zhiming, Zhang pu. The relationship between increased heart rate and autonomic nerve function in patients with hypertension[J]. 2021, (5): 356-358.
DOI：

Bai mei, Yuan zhiming, Zhang pu. The relationship between increased heart rate and autonomic nerve function in patients with hypertension[J]. 2021, (5): 356-358. DOI：

摘要

目的探讨高血压患者杓型心率

非杓型心率及预后不良者心率的变化及与心率变异(HRV)的关系以及心率增快对预后的影响。方法随机选取高血压患者164例并对134例患者进行0.5-3年的追踪随访

将选取的高血压患者分为杓型心率组、非杓型心率组、预后不良的事件组。全部做24h动态心电图监测

采集静息心率(RHR)、平均心率(AHR)、夜间心率(NHR)、昼间心率(DHR)、心率变异的低频(LF)、高频(HF)值进行分析统计。结果非杓型心率组与杓型心率组比:昼间LF减低

夜间LF、HF显著减低(p<0.05)

RHR、AHR、NHR均显著增高(p<0.001

p<0.05)。杓型心率组HRV昼夜比:夜间LF、HF明显高于昼间(p<0.05)

但LF/HF比值昼>夜。事件组与非杓型心率组比:昼夜LF、HF均显著减低(p<0.001)、RHR、AHR、NHR、DHR均显著增快(p<0.001)。结论高血压患者随着病情进行性加重

心率逐渐加快。24h平均心率大于82次/分

而HRV呈进行性减低

这种慢性心率增快是交感神经过度激活

迷走神经过度抑制

自主神经功能逐渐衰竭的结果。

Abstract

Objective To explore the variation of dipper heart rate

non-dipper heart rate and heart rate in hypertensive patients with poor prognosis and the relationship with heart rate variation（HRV） and the effect of increased heart rate on prognosis. Methods One hundred and sixty four patients with hypertension were randomly selected and 134 patients were followed up for 0.5-3 years. The patients were divided into three groups: dipper heart rate group

non-dipper heart rate group and adverse event group. All patients were monitored by 24 h Holter. Observe resting heart rate（RHR）

average heart rate（AHR）

night heart rate（NHR）

day heart rate（DHR）

HF（the quantitative index of heart rate variability） and analyzed by SPSS 15.0 Statistical software. Results Comparing Non-dipper heart rate group with dipper heart rate group. The value of LF decreased at day

and the value of LF

HF were significantly lower at night（p<0.05）; RHR

AHR

NHR were significantly higher（p<0.001

p<0.05）. Comparing night with day in group of dipper heart rate

the mean of LF

HF were significantly higher（p<0.05）

but the value of LF/HF at day was higher than that at night. Comparing the event group with the non-dipper group: LF

HF at day and night were significantly lower（p<0.001）

and RHR

AHR

NHR and DHR were significantly higher（p<0.001）.Conclusions With the progressive aggravation of hypertension patients

heart rate gradually accelerated. The 24 h average heart rate was more than 82 beats/min

and the HRV decreased progressively.This chronic heart rate increase was the result of excessive activation of the sympathetic nerve and excessive inhibition of the vagus nerve

and gradual exhaustion of autonomic nerve function.

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