The effects of continuous positive airway pressure on QT dispersion,heart rate variability and ventricular late potential in patients with severe obstructive sleep apnea

Li wen; Cheng fangzhou; Li weiguo; Chen liling; Jiang wenlong

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The effects of continuous positive airway pressure on QT dispersion,heart rate variability and ventricular late potential in patients with severe obstructive sleep apnea

更新时间：2025-10-15

- The effects of continuous positive airway pressure on QT dispersion,heart rate variability and ventricular late potential in patients with severe obstructive sleep apnea
- Issue 2, Pages: 124-127(2022)
- 作者机构：
  
  1. 深圳市盐田区人民医院
  2. 福建医科大学附属龙岩市第一医院心内科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R766
- Published：2022
- 稿件说明：
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Li wen, Cheng fangzhou, Li weiguo, et al. The effects of continuous positive airway pressure on QT dispersion,heart rate variability and ventricular late potential in patients with severe obstructive sleep apnea[J]. 2022, (2): 124-127.
DOI：

Li wen, Cheng fangzhou, Li weiguo, et al. The effects of continuous positive airway pressure on QT dispersion,heart rate variability and ventricular late potential in patients with severe obstructive sleep apnea[J]. 2022, (2): 124-127. DOI：

摘要

目的探讨持续气道正压通气（CPAP）对重度阻塞性睡眠呼吸暂停（OSA）患者QT离散度、心率变异性及心室晚电位的影响。方法收集两家医院诊断重度OSA患者182例，其中CPAP治疗组102例，拒绝CPAP治疗组80例；在接受CPAP治疗前以及CPAP治疗3个月后，所有对象均进行QT离散度（QTd）、心率变异性（HRV）及心室晚电位（VLP）的检测，统计分析比较两组间以及CPAP治疗组治疗前后的临床及心电资料数据。结果 CPAP治疗组与对照组比较，QTd较对照组缩短、HRV较对照组减小、VLP阳性比例较对照组明显减少，差别具有统计学意义，p<0.05；在CPAP治疗组中，治疗前及治疗后3个月比较，CPAP治疗组3个月后的QTd较治疗前缩短、HRV较治疗前减小、VLP阳性比例较治疗前明显减少，差别具有统计学意义，p<0.05。结论规范的CPAP治疗能有效改善重度OSA患者QTd、HRV、VLP，减少心律失常的发生及恶化。

Abstract

Objective To investigate the effects of CPAP on QT dispersion

heart rate variability and ventricular late potential in patients with severe OSA. Methods A total of 182 patients with severe OSA diagnosed in two hospitals were collected

including 102 in the CPAP treatment group and 80 in the refusal group. Before and 3 months after CPAP treatment

all subjects were measured for QT dispersion（QTD）

heart rate variability（HRV） and ventricular late potential（VLP）. Clinical and ECG data between the two groups as well as before and after CPAP treatment were statistically analyzed and compared. Results Compared with the control group

QTD

HRV and VLP positive ratio of the CPAP treatment group were shortened

decreased

and the difference was statistically significant（p<0.05）. In the CPAP treatment group

QTD

HRV and VLP positive ratio in the CPAP treatment group were shortened

decreased

and decreased significantly in the CPAP treatment group 3 months after treatment compared with before treatment

with statistical differences（p<0.05）. Conclusions Standard CPAP treatment can effectively improve QTD

HRV

VLP

and reduce the occurrence and deterioration of arrhythmia in patients with severe OSA.

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references

高血压病合并阻塞性睡眠呼吸暂停的血压昼夜节律研究[J]. 张健,惠汝太,裴卫东,赵斌,徐守春,刘力生.中华心血管病杂志,2000(01)

阻塞性睡眠呼吸暂停患者的心律失常特点及与体位变化的关系[J]. 吴学勤,叶非常,余锋,梅桢峰.中国心脏起搏与心电生理杂志,1999(02)

阻塞性睡眠呼吸暂停综合征与心律失常[J]. 牛楠,戴玉华,黄席珍.中华心血管病杂志,1997(05)

Distribution of late potentials within infarct scars assessed by ultra high-density mapping[J]. Shiro Nakahara;Roderick Tung;Rafael J. Ramirez;Jean Gima;Isaac Wiener;Aman Mahajan;Noel G. Boyle;Kalyanam Shivkumar.Heart Rhythm,2010(12)

Relationship of late potentials to the ventricular tachycardia circuit defined by entrainment.[J]. Hsia Henry H;Lin David;Sauer William H;Callans David J;Marchlinski Francis E.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing,2009(1)

Comparison of autonomic withdrawal in men with obstructive sleep apnea syndrome, systemic hypertension, and neither condition[J]. Tiina M Salo;Antti M Jula;Juhana S Piha;Ilkka M Kantola;Lisa Pelttari;Esa Rauhala;Taina H Mets?l?;Jarmo O Jalonen;Liisa-Maria Voipio-Pulkki;Jorma S.A Viikari.The American Journal of Cardiology,2000(2)

Altered cardiovascular variability in obstructive sleep apnea.[J]. Narkiewicz K;Montano N;Cogliati C;van de Borne P J;Dyken M E;Somers V K.Circulation,1998(11)

Different heart rate patterns in obstructive apneas during NREM sleep.[J]. Bonsignore M R;Romano S;Marrone O;Chiodi M;Bonsignore G.Sleep,1997(12)

[Obstructive sleep apnea as a cause of dysrhythmia in sudden cardiac death].[J]. Szabóová E;Donic V;Tomori Z;Koval S.Bratislavske lekarske listy,1997(7-8)

QT dispersion: an indication of arrhythmia risk in patients with long QT intervals.[J]. Day C P;McComb J M;Campbell R W.British Heart Journal,1990(6)

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