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目的 探讨不同类型心力衰竭患者QTc间期、QRS-T夹角及心率变异性(HRV)与心功能的相关性。方法 选取心衰患者103例,男57例,女46例,根据左心室射血分数(LVEF)分为射血分数保留的心衰(HFpEF)组43例、射血分数中间值的心衰(HFmr EF)组23例、射血分数降低的心力衰竭(HFr EF)组37例;另选取同期非心衰患者52例。完善心电图、动态心电图等相关检查。结果 心电图QTc间期及QRS-T夹角在HFmr EF组及HFr EF组显著大于对照组及HFpEF组(P<0.01);心率变异性时域指标中的SDNN、SDNNindex及三角指数在HFmr EF组及HFr EF组显著低于对照组及HFpEF组(P<0.01);但HFpEF组与对照组相比各指标差异无统计学意义(P>0.05);相关性分析显示,心衰患者LVEF与QTc间期及QRS-T夹角呈显著负相关性(r=-0.425
P<0.001; r=-0.550
P<0.001),与SDNN、SDNNindex及三角指数呈显著正相关性(r=0.454
P<0.001;r=0.276
P<0.01; r=0.410
P<0.001)。结论 心衰患者的QTc间期、QRS-T夹角及HRV与心功能存在相关性,可用于辅助判断心衰类型及指导治疗。
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