Analysis of clinical and electrocardiogram characteristics in patients with prolonged QT interval

ZHAI Suoling; WANG Juan; YANG Wenyi; HONG Jiang; LIU Shaowen

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Analysis of clinical and electrocardiogram characteristics in patients with prolonged QT interval

Clinical Research | 更新时间：2026-03-30

- Analysis of clinical and electrocardiogram characteristics in patients with prolonged QT interval
- J Clin Electrocardiol Vol. 35, Issue 1, Pages: 35-41(2026)
- 作者机构：
  
  1.200080 上海，上海市第一人民医院心内科心电图室（翟锁玲，杨文艺，洪江，刘少稳）
  2.上海市第一人民医院化验室（王娟）
- 作者简介：
- 基金信息：
- DOI：
  CLC： R541.7;R540.4+1
- Received：20 June 2024，
  
  Accepted：21 November 2025，
  
  Published：28 February 2026
- 稿件说明：
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翟锁玲, 王娟, 杨文艺, 等. 伴QT间期延长患者的临床与心电图特点分析[J]. 临床心电学杂志, 2026, 35(1): 35-41.

ZHAI Suoling,WANG Juan,YANG Wenyi,et al.Analysis of clinical and electrocardiogram characteristics in patients with prolonged QT interval[J].J Clin Electrocardiol,2026,35(01):35-41.
翟锁玲, 王娟, 杨文艺, 等. 伴QT间期延长患者的临床与心电图特点分析[J]. 临床心电学杂志, 2026, 35(1): 35-41. DOI：

ZHAI Suoling,WANG Juan,YANG Wenyi,et al.Analysis of clinical and electrocardiogram characteristics in patients with prolonged QT interval[J].J Clin Electrocardiol,2026,35(01):35-41. DOI：

摘要

目的

本文回顾分析2020年1月至2024年5月上海市第一人民医院常规及动态心电图QT间期延长病例91例。分析QT间期延长原因，心电图特点及与电解质关系。

方法

所有患者选择QRS波起点明确以及T波较为清晰的胸前导联常规测量QT间期，根据公式换算校正后的QTc间期，将91例QT间期延长患者按照电解质有无异常分为异常及正常两个组别。

结果

91例患者的QT间期，均值（492.0±22 ms），校正后的QTc间期，均值（542.03±11 ms）。91例患者中75例有电解质异常，占比82.4%；16例无电解质异常，占比17.6%。无电解质异常者中，其中2例为先天性QT间期延长患者，9例与药物使用有关，6例与心肌损伤有关。

结论

心电图QT间期延长与电解质异常相关，有明显的统计学差异。临床发现此类患者，立即检查电解质，电解质正常者部分病例要进行基因检测，病因排查。

Abstract

Objective This article retrospectively analyzed 91 cases of QT interval extension on routine and dynamic electrocardiograms in our hospital from January 2020 to May 2024. To analyze the reasons for QT prolongation

electrocardiogram characteristics

and their relationship with electrolytes. Methods All patients chose the chest lead with clear QRS wave starting point and clear T wave to measure QT interval. According to the formula

the corrected QTc interval was converted

and 91 patients with prolonged QT interval were divided into two groups according to whether the electrolyte was abnormal or not. Results Among 91 patients

75 had electrolyte abnormalities

accounting for 82.4%. Total 16 cases were unrelated to electrolyte abnormalities

accounting for 17.6%.The measured QT interval of 91 patients was (492.0 ms)

the mean value was (492.0±22 ms)

and the corrected QTc interval was (542.03ms)

the mean value was (542.03±11 ms). Two of them is a patient with congenital QT elongation. Nine cases were related to drug use

and six cases were associated with myocardial injury. Conclusions The prolongation of QT on electrocardiogram is mostly related to electrolyte abnormalities

with significant statistical differences

and some are caused by various electrolyte abnormalities. If such patients are found clinically

they should be immediately checked for electrolytes

some cases undergo genetic testing

and the cause of the disease should be investigated. Prolonged QT is a more severe clinical symptom.

关键词

Keywords

references

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