JIA Weibin,SONG Jinzhao,XIAO Jinggang,et al.A comparative study of the electrocardiographic “U-turn” phenomenon in patients with and without left heart failure[J].J Clin Electrocardiol,2026,35(01):42-47.
JIA Weibin,SONG Jinzhao,XIAO Jinggang,et al.A comparative study of the electrocardiographic “U-turn” phenomenon in patients with and without left heart failure[J].J Clin Electrocardiol,2026,35(01):42-47.DOI:
A comparative study of the electrocardiographic “U-turn” phenomenon in patients with and without left heart failure
Objective To investigate the differences in the electrocardiographic "U-turn" phenomenon between hospitalized patients with structural heart disease and with versus without left heart failure (HF). Methods In this multicenter
cross-sectional sub-study
consecutive patients with structural heart disease were enrolled from six cardiology departments (November 1
2017
to January 31
2020). Patients exhibiting the "U-turn" feature were categorized into HF and non-HF groups. ECGs were analyzed for: PTFV
1
<
-0.02 mm·s
ST-T changes or pathological Q waves
arrhythmias
notched/fragmented QRS complexes
"U-turn" slow-down
and QRS duration. Intergroup comparisons were performed for the incidence or median values of these parameters. Results Of 532 eligible patients with the "U-turn" feature
417 (78.4%) had HF and 115 (21.6%) did not. Significant intergroup differences (all
P
<
0.001) were found in: PTFV
1
<
-0.02 mm·s (71.1%
vs.
17.1%;
χ²
=96.168)
ST-T/pathological Q waves (89.2%
vs.
51.3%;
χ²
=84.202)
arrhythmias (54.4%
vs.
25.2%;
χ²
=30.827)
and notched/fragmented QRS (44.8%
vs.
26.1%;
χ²
=13.131). QRS duration also differed significantly (
Z
=-4.558
P
<
0.001). Incidences of "U-turn slow-down" (22.5%
vs.
14.8%;
χ²
=3.287
P
=0.070) and "U-turn" wave dynamic changes (
χ²
=0.002
P
=0.964) were not significantly different. Conclus
ions Among hospitalized patients with structural heart disease who exhibit the electrocardiographic "U-turn" phenomenon
the prevalence of PTFV
1
abnormality
ST-T changes or pathological Q waves
arrhythmias
notched/fragmented QRS complexes
as well as the QRS duration
are all significantly higher in those with concurrent HF than in those without.
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