目的探讨非瓣膜病房颤(NVAF)患者发生缺血性脑卒中(IS)的危险因素。方法回顾分析我院住院的NVAF患者相关临床资料
分析其IS发生的高危因素。结果 481例NVAF患者IS发生率14.55%
华法林使用率23.07%
INR达标率6.44%。多因素Logistic回归模型分析显示:高龄(OR=3.003
p=0.003)、高血压(OR=1.953
p=0.016)、糖尿病(OR=2.153
p=0.007)、左心室收缩功能减退(OR=2.201
p=0.005)、左房增大(OR=2.128
p=0.007)、持续性房颤(OR=2.309
p=0.014)是IS发生的高危因素。结论 NVAF合并高龄、高血压、糖尿病、左房增大、左心室收缩功能减退、持续性房颤增加IS的发生率。本地区INR达标率极低。
朱俊,杨艳敏.新型口服抗凝药与心房颤动血栓栓塞预防[J].中华心血管病杂志,2014(05).
伊惠霞,侯月梅,王青丽.1136例房颤患者INR监测分析[J].新疆医科大学学报,2008(10).
胡大一,孙艺红,周自强,李奎宝,倪永斌,杨光,孙淑红,李蕾.中国人非瓣膜性心房颤动脑卒中危险因素的病例-对照研究[J].中华内科杂志,2003(03).
Yutao Guo,Haijun Wang,Xiaoning Zhao,Yu Zhang,Dexian Zhang,Jingling Ma,Yutang Wang,Gregory Y.H. Lip.Relation of renal dysfunction to the increased risk of stroke and death in female patients with atrial fibrillation[J].International Journal of Cardiology,2013.
Larry B. Goldstein,Cheryl D. Bushnell,Robert J. Adams,Lawrence J. Appel,Lynne T. Braun,Seemant Chaturvedi,Mark A. Creager,Antonio Culebras,Robert H. Eckel,Robert G. Hart,Judith A. Hinchey,Virginia J. Howard,Edward C. Jauch,Steven R. Levine,James F. Meschia,Wesley S. Moore,J.V. (Ian) Nixon,Thomas A. Pearson.Guidelines for the Primary Prevention of Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association[J].Stroke,2011(2).
L. Samuel Wann,Anne B. Curtis,Craig T. January,Kenneth A. Ellenbogen,James E. Lowe,N.A. Mark Estes,Richard L. Page,Michael D. Ezekowitz,David J. Slotwiner,Warren M. Jackman,William G. Stevenson,Cynthia M. Tracy.2011 ACCF/AHA/HRS Focused Update on the Management of Patients With Atrial Fibrillation (Updating the 2006 Guideline): A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines[J].Circulation,2011(1).
Dawn O. Kleindorfer,Jane Khoury,Charles J. Moomaw,Kathleen Alwell,Daniel Woo,Matthew L. Flaherty,Pooja Khatri,Opeolu Adeoye,Simona Ferioli,Joseph P. Broderick,Brett M. Kissela.Stroke Incidence Is Decreasing in Whites But Not in Blacks: A Population-Based Estimate of Temporal Trends in Stroke Incidence From the Greater Cincinnati/Northern Kentucky Stroke Study[J].Stroke,2010(7).
Margaret C. Fang,Daniel E. Singer,Yuchiao Chang,Elaine M. Hylek,Lori E. Henault,Nancy G. Jensvold,Alan S. Go.Gender Differences in the Risk of Ischemic Stroke and Peripheral Embolism in Atrial Fibrillation: The AnTicoagulation and Risk factors In Atrial fibrillation (ATRIA) Study[J].Circulation,2005(12).
Q.I. Wen-Hang.Retrospective investigation of hospitalised patients with atrial fibrillation in mainland China[J].International Journal of Cardiology,2005(3).
Hiroshi Sohara,Shigeru Amitani,Mitsuro Kurose,Kenkichi Miyahara.Atrial Fibrillation Activates Platelets and Coagulation in a Time-Dependent Manner: A Study in Patients With Paroxysmal Atrial Fibrillation[J].Journal of the American College of Cardiology,1997(1).
Philip A. Wolf,Robert D. Abbott,William B. Kannel.Atrial Fibrillation as an Independent Risk Factor for Stroke: The Framingham Study[J].Stroke,1991(8).
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