目的通过比较常规起搏升级为心脏再同步治疗的不同疗效患者的基线特征差异
探究不同因素对升级治疗的影响。方法选取安徽省立医院心内科自2010年6月至2018年4月行常规起搏治疗(VVI、DDD、双腔ICD)升级为心脏再同步化治疗(CRT)的患者
根据其升级CRT术后6个月的反应情况将其分为有反应组和无反应组
比较两组患者的临床资料差异
并通过多因素回归分析
比较不同因素对升级心脏再同步化治疗的影响。结果共纳入56例行常规起搏治疗升级为CRT的患者
其中男性33例
女性23例
平均年龄(62.3±6.7)岁。升级CRT术后6个月
有反应者43例(76.8%)
无反应13例(23.2%)。多因素logistic回归分析显示
升级治疗前后QRS时限变化、升级前常规起搏时间是升级心脏再同步化治疗无反应的独立危险因素。无反应组患者QRS时限变化更小(p<0.01)、升级前常规起搏时间更短(p<0.05)。结论升级CRT前后的QRS时限变化、升级前的常规起搏置入时间是影响升级疗效的重要影响因素。
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